Adhesion Molecules: Function and Inhibition
Publisher: Birkhauser Basel | ISBN: 376437974X | edition 2007 | PDF | 309 pages | 10,3 mb
Publisher: Birkhauser Basel | ISBN: 376437974X | edition 2007 | PDF | 309 pages | 10,3 mb
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided.
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